- New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.
New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.
Bioorganic & medicinal chemistry letters (2007-10-09)
Mike Frohn, Han Xu, Xiaoming Zou, Catherine Chang, Michele McElvaine, Matthew H Plant, Min Wong, Philip Tagari, Randall Hungate, Roland W Bürli
PMID17920884
摘要
We report the development of the novel N-substituted benzimidazole 11 as a potent and selective human formyl peptide receptor-like 1 (hFPRL1) agonist. This compound and its less active enantiomer 12 were identified as useful tools for studying receptor function in vitro.
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