Synthesis of indoles via domino reaction of N-aryl amides and ethyl diazoacetate.

Synthesis of indoles via domino reaction of N-aryl amides and ethyl diazoacetate.

Journal of the American Chemical Society (2008-09-19)

Sun-Liang Cui, Jing Wang, Yan-Guang Wang

摘要

A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives.

材料

产品编号

品牌

产品描述

E22201

Sigma-Aldrich

重氮乙酸乙酯, contains ≥13 wt. % dichloromethane