- Improved method for the synthesis of beta-carbonyl silyl-1,3-dithianes by the double conjugate addition of 1,3-dithiol to propargylic carbonyl compounds.
Improved method for the synthesis of beta-carbonyl silyl-1,3-dithianes by the double conjugate addition of 1,3-dithiol to propargylic carbonyl compounds.
The Journal of organic chemistry (2009-11-03)
Sumit Mukherjee, Dimitra Kontokosta, Aditi Patil, Sivakumar Rallapalli, Daesung Lee
PMID19877611
摘要
Base-mediated double conjugate addition of 1,3-propane dithiol to various silylated propargylic aldehydes and ketones allows for an efficient and scalable synthesis of beta-carbonyl silyl-1,3-dithianes.