- Hair dye related acute kidney injury--a clinical and experimental study.
Hair dye related acute kidney injury--a clinical and experimental study.
Renal failure (2012-06-12)
Yanala Sandeep Reddy, Shaik Abbdul Nabi, Chippada Apparao, Chinthamaneni Srilatha, Yadla Manjusha, Parvathina Sri Ram Naveen, Chennu Krishna Kishore, Anappindi Sridhar, Vishnubotla Siva Kumar
PMID22680304
摘要
We studied paraphenylenediamine (PPD)-related acute kidney injury (AKI) in 81 patients and also in albino rats experimentally. In the patients' group AKI was found in 32.7%. Of them, 81.4% needed dialysis support. The overall mortality was 25.9%. In experimental rats the renal lesions were noted in all and they were glomerular congestion, intertubular (interstitial) hemorrhages, acute tubular necrosis, mesangial proliferation, and intratubular casts. The severity of renal injury appears to be dose dependent.