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  • Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin.

Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin.

JAMA dermatology (2013-11-29)
Megan Brown, Angela Hernández-Martín, Ana Clement, Isabel Colmenero, Antonio Torrelo
摘要

There is a limited therapeutic armamentarium for recalcitrant cases of childhood rosacea. We report the case of a 12-year-old girl who presented with severe ocular and cutaneous rosacea unresponsive to oral doxycycline, oral isotretinoin, and topical tacrolimus. A biopsy specimen showed numerous mites within the folliculosebaceous unit. Treatment with a single dose of oral ivermectin achieved resolution of her symptoms. The causative role of Demodex folliculorum should be considered in immunocompetent children with rosacea or rosacea-like refractory eruptions. In such cases, treatment with ivermectin can be beneficial.

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伊维菌素, European Pharmacopoeia (EP) Reference Standard