Effects of aspartame and phenylalanine on meal-time food intake of humans.

This article reviews data relevant to the hypothesis that aspartame may have a unique effect on meal-time food intake regulation due to its amino acid composition and in addition to its effects as a high intensity sweetener. It is concluded that future studies involving aspartame should be directed towards developing a fundamental understanding of the effects of high intensity sweeteners on food intake, and not give undue attention to putative actions based on its amino acid constituents.