Chromium exposure and germinal embryonal carcinoma: first two cases and review of the literature.

Chromium exposure and germinal embryonal carcinoma: first two cases and review of the literature.

Journal of toxicology and environmental health. Part A (2014-11-27)

Rossana Berardi, Chiara Pellei, Gianluca Valeri, Mirco Pistelli, Azzurra Onofri, Francesca Morgese, Miriam Caramanti, Riccardo Mashadi Mirza, Matteo Santoni, Mariagrazia De Lisa, Agnese Savini, Zelmira Ballatore, Gian Marco Giuseppetti, Stefano Cascinu

PMID25424542

摘要

The aim of the study was to determine the potential role of occupational exposures to chromium (Cr) in the onset of extragonadal germinal embryonal carcinoma. The first two cases of workers in a company with Cr exposure are reported. The published scientific literature regarding the topic in peer-reviewed journals including MEDLINE and CancerLit databases was extensively reviewed. Two young patients who were coworkers in the same company, exposed to Cr, developed extragonadal germinal embryonal carcinomas. One of them also developed angiosarcoma of the mediastinum. To the best of our knowledge these are the first two cases of germinal embryonal carcinoma in patients with occupational exposure to Cr.

材料

产品编号

品牌

产品描述

P4394

Sigma-Aldrich

顺铂, crystalline

266299

Sigma-Aldrich

铬, powder, ≥99% trace metals basis, <45 μm

C2210000

顺氯氨铂, European Pharmacopoeia (EP) Reference Standard

479306

Sigma-Aldrich

顺二氯化二胺（II）, ≥99.9% trace metals basis

266264

Sigma-Aldrich

铬, powder, 99.5%, −100 mesh

374849

Sigma-Aldrich

铬, chips, 99.995% trace metals basis

255610

Sigma-Aldrich

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