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Identification of new synthetic PDE-5 inhibitors analogues found as minor components in a dietary supplement.

Identification of new synthetic PDE-5 inhibitors analogues found as minor components in a dietary supplement.

Journal of pharmaceutical and biomedical analysis (2014-04-15)

Nicholas Schramek, Uwe Wollein, Wolfgang Eisenreich

摘要

A dietary supplement sold in erotic shops was analysed. It contains dithiodesmethylcarbodenafil as the major component, which was already reported as an adulterant in dietary supplements. Additionally three more compounds were found and their structures were elucidated after isolation using NMR and mass spectroscopy. They were designated as isonitrosoprodenafil, dithiodesethylcarbodenafil and norcarbodenafil.

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