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Synthesis and selected immunological properties of 10-substituted 1,8-diazaphenothiazines.

Synthesis and selected immunological properties of 10-substituted 1,8-diazaphenothiazines.

Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents (2015-03-10)

Beata Morak-Młodawska, Krystian Pluta, Michał Zimecki, Małgorzata Jeleń, Jolanta Artym, Maja Kocięba

摘要

A new type of tricyclic azaphenothiazines-1,8-diazaphenothiazines-was obtained in the reaction of 2,3- and 3,4-disubstituted pyridines. The reaction ran as the Smiles rearrangement. The 1,8-diazaphenothiazine system was determined using NOE experiment and 2D NMR spectra (COSY, HSQC, HMBC). 10

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