CLEC5A is a critical receptor in innate immunity against Listeria infection.

CLEC5A is a critical receptor in innate immunity against Listeria infection.

Nature communications (2017-08-22)

Szu-Ting Chen, Fei-Ju Li, Tzy-Yun Hsu, Shu-Mei Liang, Yi-Chen Yeh, Wen-Yu Liao, Teh-Ying Chou, Nien-Jun Chen, Michael Hsiao, Wen-Bin Yang, Shie-Liang Hsieh

PMID28824166

摘要

The C-type lectin member 5A (CLEC5A) is a pattern recognition receptor for members of the Flavivirus family and has critical functions in response to dengue virus and Japanese encephalitis virus. Here we show that CLEC5A is involved in neutrophil extracellular trap formation and the production of reactive oxygen species and proinflammatory cytokines in response to Listeria monocytogenes. Inoculation of Clec5a

材料

产品编号

品牌

产品描述

C5138

Sigma-Aldrich

胶原酶来源于溶组织梭菌, suitable for release of physiologically active rat hepatocytes, Type IV, 0.5-5.0 FALGPA units/mg solid, ≥125 CDU/mg solid

D5025

Sigma-Aldrich

脱氧核糖核酸酶 I 来源于牛胰腺, Type IV, lyophilized powder, ≥2,000 Kunitz units/mg protein

H0164

Sigma-Aldrich

抗组蛋白 H3 兔抗, IgG fraction of antiserum, buffered aqueous solution