Protein kinase- and lipase inhibitors of inositide metabolism deplete IP

Protein kinase- and lipase inhibitors of inositide metabolism deplete IP

Cellular signalling (2017-10-19)

Subu Surendran Rajasekaran, Christopher Illies, Stephen B Shears, Huanchen Wang, Thais S Ayala, Joilson O Martins, Elisabetta Daré, Per-Olof Berggren, Christopher J Barker

PMID29042286

摘要

Inositol pyrophosphates have emerged as important regulators of many critical cellular processes from vesicle trafficking and cytoskeletal rearrangement to telomere length regulation and apoptosis. We have previously demonstrated that 5-di-phosphoinositol pentakisphosphate, IP

材料

产品编号

品牌

产品描述

A3854

Sigma-Aldrich

抗-β-肌动蛋白−过氧化物酶抗体，小鼠单克隆小鼠抗, clone AC-15, purified from hybridoma cell culture

662035

Sigma-Aldrich

U-73122, U-73122, CAS 112648-68-7, inhibits agonist-induced phospholipase C activation (IC50 = 1-2.1 µM) in human platelets and neutrophils.

T0826

Sigma-Aldrich

叔丁基溴, ≥98% (HPLC), solid

HPA040825

Sigma-Aldrich

Anti-IP6K1 antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

406170

Sigma-Aldrich

IP6K Inhibitor, The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K.