Merck
CN

GABRA2

gamma-aminobutyric acid (GABA) A receptor, alpha 2

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(2555) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14395) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
  • Rat(289606) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • cow(282236) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • chicken(770511) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • naked mole-rat(101720776) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic guinea pig(100720796) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic cat(100286789) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Domestic Rabbit(100339376) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • sheep(101121265) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Horse(100061914) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • dog(482131) gamma-aminobutyric acid (GABA) A receptor, alpha 2

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Small Molecule - Agonist

货号
说明
物种
(±)-巴氯芬, ≥98% (TLC), solid,
物种
human, rat
蝇蕈醇 氢溴酸盐, ≥98% (HPLC), solid,
物种
human
Piperidine-4-sulfonic acid, ,
物种
human
加波沙朵 盐酸盐, solid, ≥98% (HPLC),
物种
human
γ-氨基丁酸, ≥99%,
物种
human, rat

Small Molecule - Allosteric Modulator

货号
说明
物种
丙泊酚标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
司可巴比妥 钠盐, ,
物种
human
普鲁泊福, European Pharmacopoeia (EP) Reference Standard,
物种
human
Prazepam, European Pharmacopoeia (EP) Reference Standard,
物种
human
丙泊酚, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human

Small Molecule - Antagonist

货号
说明
物种
2-吡咯烷酮, ≥99%,
物种
2-吡咯烷酮, 99%,
物种
2-吡咯烷酮, purum, ≥98.0% (GC),
物种
6-甲氧基黄酮, 99%,
物种
β-萘黄酮, ≥98%,
物种

Antibodies

货号
说明
物种反应性
应用
Anti-GABA(A) Receptor α2 Antibody, clone N399/19, clone N399/19, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Monoclonal Anti-GABA A Receptor-Biotin antibody produced in mouse, clone S399-19,
物种反应性
human, rat
应用
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-PerCP antibody produced in mouse, clone S399-19,
物种反应性
human, rat
应用
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Horseradish Peroxidase antibody produced in mouse, clone S399-19,
物种反应性
human, rat
应用
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 390 antibody produced in mouse, clone S399-19,
物种反应性
human, rat
应用
immunofluorescence
western blot

Small Molecule - Inhibitor

货号
说明
物种
黄酮, ≥99.0%,
物种
human, rat, mouse
柯因, 97%,
物种
human, mouse
(±)-Vigabatrin, ,
物种
human
NO-711 hydrochloride, ≥98% (HPLC),
物种
human
丙泊酚, 97%,
物种
human

Small Molecule - Ligand

货号
说明
物种
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
Ganaxolone, solid, ≥98% (HPLC),
物种
human, mouse

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GABRA2,
物种
human
MISSION® esiRNA, targeting mouse Gabra2,
物种
mouse