Merck
CN

GABBR2

gamma-aminobutyric acid (GABA) B receptor, 2

别名:
GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099
物种:
Human GABBR2 (9568), Mouse Gabbr2 (242425), Rat Gabbr2 (83633), domestic guinea pig Gabbr2 (100170764), naked mole-rat Gabbr2 (101719923), Horse GABBR2 (100063963), sheep GABBR2 (101103544), Domestic Rabbit GABBR2 (100346845), domestic cat GABBR2 (101093058), cow GABBR2 (517040) ...展开
UniProtKB ID:
O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9
基因ID:
  • Human(9568) Summary: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
  • Mouse(242425) gamma-aminobutyric acid (GABA) B receptor, 2
  • Rat(83633) gamma-aminobutyric acid (GABA) B receptor 2
  • domestic guinea pig(100170764) gamma-aminobutyric acid (GABA) B receptor, 2
  • naked mole-rat(101719923) gamma-aminobutyric acid (GABA) B receptor, 2
  • Horse(100063963) gamma-aminobutyric acid (GABA) B receptor, 2
  • sheep(101103544) gamma-aminobutyric acid (GABA) B receptor, 2
  • Domestic Rabbit(100346845) gamma-aminobutyric acid (GABA) B receptor, 2
  • domestic cat(101093058) gamma-aminobutyric acid (GABA) B receptor, 2
  • cow(517040) gamma-aminobutyric acid (GABA) B receptor, 2
  • dog(481627) gamma-aminobutyric acid (GABA) B receptor, 2
  • Zebrafish(560267) gamma-aminobutyric acid (GABA) B receptor, 2
  • chicken(420979) gamma-aminobutyric acid (GABA) B receptor, 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

货号
说明
物种
PHR1682
巴氯芬, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
1048200
(±)-巴氯芬, United States Pharmacopeia (USP) Reference Standard,
物种
human
B0200000
巴氯芬, European Pharmacopoeia (EP) Reference Standard,
物种
human
B-071
巴氯芬 溶液, 500 μg/mL (90:10 MeOH:DMSO), certified reference material, ampule of 1 mL, Cerilliant®,
物种
human
BP028
巴氯芬, British Pharmacopoeia (BP) Reference Standard,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
C0987
CGP-13501, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
P118
法洛芬, solid,
物种
human
A6566
2-羟色胺, ≥98% (TLC), solid,
物种
human
B5399
(±)-巴氯芬, ≥98% (TLC), solid,
物种
human, rat
S166
Saclofen, solid,
物种
mouse, human, rat
A2129
γ-氨基丁酸, ≥99%,
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
AB2255
抗-GABA B受体R2抗体, serum, from guinea pig,
物种反应性
bovine, canine, chimpanzee, horse, human, mouse, rat, rhesus macaque, rhesus monkey
应用
immunohistochemistry
western blot
MABN740
Anti-GABA-B receptor 2 Antibody, clone N81/37, clone N81/37, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
HPA013820
Anti-GABBR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
G9920
Anti-GABAB Receptor 2 兔抗, affinity isolated antibody, lyophilized powder,
物种反应性
rat
应用
western blot
SAB4701034
Anti-GABA(B) R2 antibody produced in rabbit, ,
物种反应性
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
N142
NO-711 hydrochloride, ≥98% (HPLC),
物种
human
V8261
(±)-Vigabatrin, ,
物种
human

esiRNA

货号
说明
物种
EHU002331
MISSION® esiRNA, targeting human GABBR2,
物种
human