MMP20
matrix metallopeptidase 20
别名:
AI2A2, MMP-20
物种:
Human MMP20 (9313), Mouse Mmp20 (30800), Rat Mmp20 (300341), cow MMP20 (281916), sheep MMP20 (101119666), domestic cat MMP20 (101080734), domestic guinea pig Mmp20 (100719984), naked mole-rat Mmp20 (101717548), dog MMP20 (611829)
UniProtKB ID:
基因ID:
- Human(9313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3. [provided by RefSeq, Aug 2011]
- Mouse(30800) matrix metallopeptidase 20 (enamelysin)
- Rat(300341) matrix metallopeptidase 20
- cow(281916) matrix metallopeptidase 20
- sheep(101119666) matrix metallopeptidase 20
- domestic cat(101080734) matrix metallopeptidase 20
- domestic guinea pig(100719984) matrix metallopeptidase 20
- naked mole-rat(101717548) matrix metallopeptidase 20
- dog(611829) matrix metallopeptidase 20
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