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N158

Naftopidil hydrochloride hydrate

solid

别名:

4-(2-Methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-1-piperazineethanol hydrochloride hydrate, KT-611

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关于此项目

经验公式（希尔记法）:
C24H28N2O3 · xHCl · yH2O
化学文摘社编号:
57149-07-2
分子量:
392.49 (anhydrous free base basis)
NACRES:
NA.77
PubChem Substance ID:
24277790
UNSPSC Code:
12352200
MDL number:
MFCD11046013
Form:
solid
Quality level:
200
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form

solid

Quality Level

200

color

white

solubility

methanol: >10 mg/mL, H2O: insoluble

SMILES string

O.Cl.COc1ccccc1N2CCN(CC2)CC(O)COc3cccc4ccccc34

InChI

1S/C24H28N2O3.ClH.H2O/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23;;/h2-12,20,27H,13-18H2,1H3;1H;1H2

InChI key

INIDYCYXDNFBSV-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Biochem/physiol Actions

α1-Adrenoceptor antagonist; antihypertensive.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000329566
0000329583
0000329583
0000329566
SLCM9335

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Katsumi Kadekawa et al.
Life sciences, 92(20-21), 1024-1028 (2013-04-16)
Alpha1D-adrenoceptors (α1D-ARs) located in the spinal cord are involved in the control of lower urinary tract function. In order to clarify the effect of α1D-ARs on storage function in the spinal cord, we examined the effect of oral administration and
Xiawen Liu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 907, 140-145 (2012-10-03)
Two bioanalytical HPLC methods (chiral solid phases (CSPs) HPLC and pre-column derivatization HPLC) were developed and validated for the determination of naftopidil enantiomers in rat plasma. Analytes were extracted from biomaterials by liquid-liquid extraction. The pre-column derivatization HPLC method employed
Tomokazu Sazuka et al.
Journal of endourology, 26(9), 1216-1220 (2012-04-11)
To examine the efficacy of an alpha-1 blocker and its correlation to structural alteration of the prostatic urethra and the loss of energy in the urine flow using a virtual urethra processed from an endoscopic video image. Video images of
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全球贸易项目编号

货号GTIN
N158-100MG04061832092218
N158-25MG04061832092225