Merck
CN

GABRA2

gamma-aminobutyric acid (GABA) A receptor, alpha 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2555) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14395) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
  • Rat(289606) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • cow(282236) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • chicken(770511) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • naked mole-rat(101720776) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic guinea pig(100720796) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • domestic cat(100286789) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Domestic Rabbit(100339376) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • sheep(101121265) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • Horse(100061914) gamma-aminobutyric acid (GABA) A receptor, alpha 2
  • dog(482131) gamma-aminobutyric acid (GABA) A receptor, alpha 2

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Small Molecule - Agonist

Product Number
Description
Species
(±)-Baclofen, ≥98% (TLC), solid,
Species
human, rat
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
Piperidine-4-sulfonic acid, ,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Thiopental, United States Pharmacopeia (USP) Reference Standard,
Species
human
Oxazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Triazolam, European Pharmacopoeia (EP) Reference Standard,
Species
human
Propofol, European Pharmacopoeia (EP) Reference Standard,
Species
human
Propofol, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
β-Naphthoflavone, ≥98%,
Species
2-Pyrrolidinone, purum, ≥98.0% (GC),
Species
2-Pyrrolidinone, 99%,
Species
2-Pyrrolidinone, ≥99%,
Species
6-Methoxyflavone, 99%,
Species

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GABA A Receptor-Allophycocyanin antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-FITC antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Horseradish Peroxidase antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 390 antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 594 antibody produced in mouse, clone S399-19,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Flavone, ≥99.0%,
Species
human, rat, mouse
Chrysin, 97%,
Species
human, mouse
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
(±)-Vigabatrin, ,
Species
human
2,6-Diisopropylphenol, 97%,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Ganaxolone, solid, ≥98% (HPLC),
Species
human, mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gabra2,
Species
mouse
MISSION® esiRNA, targeting human GABRA2,
Species
human