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488216

Sigma-Aldrich

3,4-Dihydroxy-1-butene

≥99%

Synonym(s):

3-Butene-1,2-diol

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About This Item

Linear Formula:
CH2=CHCH(OH)CH2OH
CAS Number:
497-06-3
Molecular Weight:
88.11
Beilstein:
1633578
EC Number:
207-835-1
MDL number:
MFCD00239410
UNSPSC Code:
12352100
PubChem Substance ID:
24872379
NACRES:
NA.22

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Quality Level

100

Assay

≥99%

bp

195 °C/733 mmHg (lit.)

density

1.047 g/mL at 25 °C (lit.)

functional group

hydroxyl

SMILES string

OCC(O)C=C

InChI

1S/C4H8O2/c1-2-4(6)3-5/h2,4-6H,1,3H2

InChI key

ITMIAZBRRZANGB-UHFFFAOYSA-N

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This Item
239267381926216135
Cobalt(II) phthalocyanine β-form, Dye content 97 %

307696

Cobalt(II) phthalocyanine

Cobalt(II) nitrate hexahydrate ACS reagent, ≥98%

239267

Cobalt(II) nitrate hexahydrate

Cobalt(II) 2,3-naphthalocyanine Dye content 85 %

381926

Cobalt(II) 2,3-naphthalocyanine

Cobalt(II) thiocyanate 96%

216135

Cobalt(II) thiocyanate

form

powder

form

chips, powder, crystals or chunks, solid

form

-

form

powder

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

100

composition

Dye content, 97%

composition

-

composition

Dye content, 85%

composition

-

General description

3,4-Dihydroxy-1-butene, also known as 3-butene-1,2-diol (BDdiol), is a metabolite of 1,3-butadiene.[1] It forms the precursor for synthesizing different chiral building blocks.[2] BDdiol can undergo oxidation to form hydroxymethylvinyl ketone (HMVK).[3] 1,2-epoxy-3-butene (EB) on hydrolysis in the presence of epoxide hydrolases (EH) forms BDdiol.[4]

Application

3,4-Dihydroxy-1-butene can be used:
  • As a reactant to synthesize cyclic organic carbonates by continuous flow procedure.[5]
  • To prepare substituted oxazolidinone ligands used to target medicinally relevant RNAs.[6]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

常规特殊物品
含少量动物源组分生物产品

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