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EMU071431

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Stk35

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AAAGGATCCTGGGCTATGCTGAGGAGCCCTGCTATCTCTGGTTTGTCATGGAGTACTGTGAAGGTGGAGACCTCAATCAGTATGTCCTGTCCCGGAGAGCTGACCCAGCCACCAACAAAAGTGTCATGCTACAGCTTACAAGCGCCATTGCCTTCCTGCATAAAAACCACATCGTGCACAGGCGACCTAAAGCCAGACAACATCCTGATCACAGAGCGGTCGGCACCCCCATCCTCAAGGTGGCAGACTTTGGACTGAGCAAGGTCTGTGCAGGGCTGGCACCCCGAGGCAAAGAGGGCAATCAAGATAACAAAAATGTGAATGTGAATAAATACTGGCTGTCCTCAGCTTGTGGCTCAGACTTCTACATGGCTCCCGAAGTCTGGGAGGGACACTACACAGCCAAGGCGGACATCTTTGCTCTGGGCAT

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... Stk35(67333)

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form

foil

form

foil

form

foil

form

foil

assay

≥99.6%

assay

≥99.6%

assay

≥99.6%

assay

≥99.6%

bp

3287 °C (lit.)

bp

3287 °C (lit.)

bp

3287 °C (lit.)

bp

3287 °C (lit.)

density

4.5 g/mL at 25 °C (lit.)

density

4.5 g/mL at 25 °C (lit.)

density

4.5 g/mL at 25 °C (lit.)

density

4.5 g/mL at 25 °C (lit.)

resistivity

42.0 μΩ-cm, 20°C

resistivity

42.0 μΩ-cm, 20°C

resistivity

42.0 μΩ-cm, 20°C

resistivity

42.0 μΩ-cm, 20°C

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Magdalena Kotańska et al.
    Biochemical pharmacology, 168, 193-203 (2019-07-12)
    Histamine H3 receptors ligands act anorectic by blocking the H3 autoreceptors in the CNS, that results in increased synthesis and disinhibition of histamine release. Histamine further influencing H1 receptors participates in the leptin-dependent inhibition of food intake. It also affects
    Structure-activity relations of histamine analogs. XX. Absolute configuration and histamine-like activity of enantiomeric α-methyl histamines.
    Gerhard, et al.
    Archives of Pharmacal Research, 313, 709-709 (1980)
    J M Arrang et al.
    Nature, 327(6118), 117-123 (1987-05-14)
    New drugs selective for histamine H3-receptors can be used to establish that these receptors are involved in the feedback control of histamine synthesis and release, and to demonstrate their distribution in the brain and peripheral tissues. These drugs provide new
    R Oishi et al.
    Journal of neurochemistry, 52(5), 1388-1392 (1989-05-01)
    To study the feedback control by histamine (HA) H3-receptors on the synthesis and release of HA at nerve endings in the brain, the effects of a potent and selective H3-agonist, (R)-alpha-methylhistamine, and an H3-antagonist, thioperamide, on the pargyline-induced accumulation of
    Xu-Dong Wang et al.
    Nature communications, 10(1), 3201-3201 (2019-07-22)
    Pulmonary neuroendocrine (NE) cancer, including small cell lung cancer (SCLC), is a particularly aggressive malignancy. The lineage-specific transcription factors Achaete-scute homolog 1 (ASCL1), NEUROD1 and POU2F3 have been reported to identify the different subtypes of pulmonary NE cancers. Using a

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