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IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

别名:
IMPD2, IMPDH-II
物种:
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), dog IMPDH2 (476630), Zebrafish impdh2 (317745), domestic guinea pig Impdh2 (100730768), naked mole-rat Impdh2 (101701391), domestic cat IMPDH2 (101080693), cow IMPDH2 (511969), sheep IMPDH2 (101107823) ...展开
UniProtKB ID:
P12268, Q6LEF3
基因ID:
  • Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
  • Mouse(23918) inosine 5'-phosphate dehydrogenase 2
  • Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
  • domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2

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Antibodies

Product Number
说明
物种反应性
应用
HPA001400
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
WH0003615M1
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)
western blot
ST1578
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
物种反应性
human
应用
SAB1406037
Anti-IMPDH2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
SAB1410715
Anti-IMPDH2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
说明
物种
N4505
还原型 β-烟酰胺腺嘌呤二核苷酸 二钾盐, ,
物种
human
A4882
6-硫代鸟嘌呤, ≥98%,
物种
human
R9644
利巴韦林, antiviral,
物种
human
1448956
霉酚酸酯, United States Pharmacopeia (USP) Reference Standard,
物种
human
A4660
6-硫代鸟嘌呤, Hybri-Max™, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
物种
human

Proteins

Product Number
说明
物种
I1782
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
物种
human

esiRNA

Product Number
说明
物种
EMU094871
MISSION® esiRNA, targeting mouse Impdh2,
物种
mouse
EHU027541
MISSION® esiRNA, targeting human IMPDH2,
物种
human