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Merck
CN

06372

β-Hydroxypyruvic acid

≥95.0% (dry substance, T)

别名:

3-羟基-2-氧代丙酸

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关于此项目

经验公式(希尔记法):
C3H4O4
化学文摘社编号:
分子量:
104.06
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
Assay:
≥95.0% (dry substance, T)
Form:
powder and chunks
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Quality Level

assay

≥95.0% (dry substance, T)

form

powder and chunks

impurities

≤15.0% water

storage temp.

2-8°C

InChI

1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7)

InChI key

HHDDCCUIIUWNGJ-UHFFFAOYSA-N

Application


  • 总状升麻中的羟基(苯基)丙酮酸还原酶:升麻酸和蜂斗菜酸生物合成中的假定酶。: 本研究考察了β-羟基丙酮酸在总状升麻中生物活性化合物生物合成中的作用,重点介绍了其在植物次生代谢中的重要性及其在药物化学中的潜在应用(Jahn and Petersen, 2024)。

  • 肠道微生物群可以保护中枢神经系统免受锰中毒引起的神经退行性变。: 研究表明肠道微生物群产生的β-羟基丙酮酸衍生物可以保护人们免于罹患神经退行性疾病,提供了有关神经系统疾病治疗策略的见解(Wang et al., 2020)。

Biochem/physiol Actions

参与光呼吸中碳途径的代谢产物


pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Seong Pil Chung et al.
Journal of biochemistry, 148(6), 743-753 (2010-09-30)
D-amino acid oxidase (DAO) is a flavoenzyme that exists in the kidney, liver and brain of mammals. This enzyme catalyzes the oxidation of D-amino acids to the corresponding α-keto acid, hydrogen peroxide and ammonia. Recently D-serine, one of the substrates
O A Esakova et al.
IUBMB life, 59(2), 104-109 (2007-04-25)
The interaction of thiamine diphosphate (ThDP) with transketolase (TK) involves at least two stages: [formula: see text] During the first stage, an inactive intermediate complex (TK...ThDP) is formed, which is then transformed into a catalytically active holoenzyme (TK* - ThDP).
William E Karsten et al.
Biochimica et biophysica acta, 1790(6), 575-580 (2009-03-07)
The enzyme L-serine-glyoxylate aminotransferase (SGAT) from Hyphomicrobium methylovorum is a PLP-containing enzyme that catalyzes the conversion of L-serine and glyoxylate to hydroxypyruvate and glycine. The cloned enzyme expressed in Escherichia coli is isolated as a mixture of the E:PLP and



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