12804
苯并三氮唑-N,N,N′,N′-四甲基脲六氟磷酸酯
≥98.0% (T), for peptide synthesis
别名:
N,N,N′,N′-四甲基-O-(1H-苯并三氮唑)六氟磷酸脲, HBTU
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C11H16F6N5OP
化学文摘社编号:
分子量:
379.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352107
EC Number:
423-020-5
MDL number:
Beilstein/REAXYS Number:
7328329
产品名称
苯并三氮唑-N,N,N′,N′-四甲基脲六氟磷酸酯, ≥98.0% (T)
InChI key
UQYZFNUUOSSNKT-UHFFFAOYSA-N
InChI
1S/C11H16N5O.F6P/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1
SMILES string
F[P-](F)(F)(F)(F)F.CN(C)C(\On1nnc2ccccc12)=[N+](/C)C
assay
≥98.0% (T)
form
solid
reaction suitability
reaction type: Coupling Reactions
mp
200 °C (dec.) (lit.)
solubility
acetonitrile: 0.1 g/mL, clear
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
HBTU是用于多肽合成的多肽偶联剂。它也被用于标准Fmoc固相多肽合成（SPPS）方案。
最近研究显示，这种偶联试剂的结晶或溶液结构是胍的 N-氧化物形式，,而不是脲化合物； 用于多肽合成的偶联试剂；优点是：极低的外消旋化，简单的反应条件，非常短的反应时间和高产率。
General description
HBTU是一种肽偶联剂，用于基于Fmoc的固相肽合成。
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1A
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Small molecule approach to studying protein tyrosine phosphatase.
Kumar S, et al.
Methods, 35(1), 9-21 (2005)
One-step 18 F-labeling of peptides for positron emission tomography imaging using the SiFA methodology.
Wangler C, et al.
Nature Protocols, 7(11), 1946-1946 (2012)
Some mechanistic aspects on Fmoc solid phase peptide synthesis
Pires DAT, et al.
International Journal of Peptide Research and Therapeutics, 20, 53-69 (2014)
Héloise Boullet et al.
Molecules (Basel, Switzerland), 24(9) (2019-05-06)
Antimicrobial peptides (AMPs) are considered as potential therapeutic sources of future antibiotics because of their broad-spectrum activities and alternative mechanisms of action compared to conventional antibiotics. Although AMPs present considerable advantages over conventional antibiotics, their clinical and commercial development still
Mark Lommel et al.
Scientific reports, 8(1), 11753-11753 (2018-08-08)
Thrombospondins (TSPs) are multidomain glycoproteins with complex matricellular functions in tissue homeostasis and remodeling. We describe a novel role of TSP as a Wnt signaling target in the basal eumetazoan Hydra. Proteome analysis identified Hydra magnipapillata TSP (HmTSP) as a
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持