15456
Boc-Lys-OH
≥99.0% (NT)
别名:
Nα-(叔丁氧羰基)-L-赖氨酸, Nα-Boc-L-赖氨酸
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关于此项目
线性分子式:
NH2(CH2)4CH(COOH)NHCOOC(CH3)3
化学文摘社编号:
分子量:
246.30
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
237-303-4
MDL number:
Beilstein/REAXYS Number:
4252546
产品名称
Boc-Lys-OH, ≥99.0% (NT)
Quality Level
InChI key
DQUHYEDEGRNAFO-QMMMGPOBSA-N
InChI
1S/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1
SMILES string
CC(C)(C)OC(=O)N[C@@H](CCCCN)C(O)=O
assay
≥99.0% (NT)
form
solid
optical activity
[α]20/D +4.6±0.5°, c = 2% in H2O
reaction suitability
reaction type: Boc solid-phase peptide synthesis
mp
~205 °C (dec.) (lit.)
application(s)
peptide synthesis
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Application
Boc-Lys-OH is used as a building block to form peptides that have bioorthogonal reactive groups via boc protected solid phase synthesis.
General description
Boc-Lys-OH also known as Nα-Boc-L-lysine, is an amino acid derivative of lysine which is used in solid phase peptide synthesis.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis
BM Zeglis
ChemistryOpen, 3, 48-53 (2014)
Mingqian Tan et al.
Pharmaceutical research, 31(6), 1469-1476 (2013-03-09)
To synthesize and evaluate a peptide targeted nanoglobular dual modal imaging agent specific to a cancer biomarker in tumor stroma for MRI and fluorescence visualization of prostate tumor in image-guided surgery. A peptide (CGLIIQKNEC, CLT1) targeted generation 2 nanoglobular (polylysine
Katherine A Miller et al.
Journal of bacteriology, 197(17), 2831-2839 (2015-06-24)
Salmonella enteric serovar Typhimurium, a major cause of food-borne illness, is capable of using a variety of carbon and nitrogen sources. Fructoselysine and glucoselysine are Maillard reaction products formed by the reaction of glucose or fructose, respectively, with the ε-amine
Griet Van Zeebroeck et al.
Nature chemical biology, 5(1), 45-52 (2008-12-09)
Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid analogs to identify compounds that act on Gap1
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