191140
7-氨基头孢烷酸
98%
别名:
7-ACA
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关于此项目
经验公式（希尔记法）:
C10H12N2O5S
化学文摘社编号:
分子量:
272.28
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-485-0
Beilstein/REAXYS Number:
622637
MDL number:
产品名称
7-氨基头孢烷酸, 98%
InChI key
HSHGZXNAXBPPDL-HZGVNTEJSA-N
InChI
1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1
SMILES string
[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2N)C(O)=O
assay
98%
form
powder
optical activity
[α]19/D +90°, c = 0.5 in KH2PO4/trace NaOH
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
antibiotic activity spectrum
Gram-positive bacteria
application(s)
peptide synthesis
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
Quality Level
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Application
7-氨基头孢烷酸（7-ACA）可用作制备以下物质的原料：
- 在三乙胺存在的情况下与 S-苯并噻唑-2-基（2-氨基-4-噻唑基）（甲氧基亚氨基）硫代乙酸酯 （MAEM）反应合成的头孢噻肟 。
- 通过头孢噻肟中间体合成的第三代抗生素头孢泊肟酯。
- 作为β-内酰胺酶潜在抑制剂的3′-取代头孢菌素钠砜衍生物。
细菌（金黄色葡萄球菌）β-内酰胺酶的有效抑制剂。
General description
化学结构:β-内酰胺
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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