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7-氨基-4-（三氟甲氧基）香豆素
≥99%
别名:
香豆素 151
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关于此项目
经验公式（希尔记法）:
C10H6F3NO2
化学文摘社编号:
分子量:
229.16
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
258-599-1
Beilstein/REAXYS Number:
4456797
MDL number:
InChI key
JBNOVHJXQSHGRL-UHFFFAOYSA-N
InChI
1S/C10H6F3NO2/c11-10(12,13)7-4-9(15)16-8-3-5(14)1-2-6(7)8/h1-4H,14H2
SMILES string
Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1
assay
≥99%
form
(Powder or Crystals or Chunks)
technique(s)
titration: suitable
mp
221-222 °C (lit.)
λmax
≤207 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
适于用作激光染料
General description
7-氨基-4-（三氟甲基）香豆素（AFC）是用于检测蛋白酶的一种新型荧光标记物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
E D Pederson et al.
Journal of clinical periodontology, 21(8), 519-525 (1994-09-01)
Treponema denticola (Td) and Porphyromonas gingivalis (Pg) are associated with human moderate and severe adult periodontal diseases. This study quantifies these two anaerobes and their trypsin-like (TL) activities in subgingival plaque collected from both clinically healthy and periodontally diseased sites
Synthesis and chemistry of 7-amino-4-(trifluoromethyl)coumarin and its amino acid and peptide derivatives
Bissell E R
The Journal of Organic Chemistry, 45, 2283?2287-2283?2287 (1980)
Franziska Ebert et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 61, 126563-126563 (2020-06-13)
Arsenolipids, especially arsenic-containing hydrocarbons (AsHC), are an emerging class of seafood originating contaminants. Here we toxicologically characterize a recently identified oxo-AsHC 332 metabolite, thioxo-AsHC 348 in cultured human liver (HepG2) cells. Compared to results of previous studies of the parent
S W Cox et al.
Archives of oral biology, 32(9), 599-605 (1987-01-01)
The cysteine proteinases cathepsins B and L have collagenolytic potential and so have been implicated in connective-tissue breakdown in chronic periodontitis. Synthetic peptide substrates are often used to detect proteolytic enzymes. The action of homogenates of inflamed gingiva tissue against
Zhimin Tao et al.
Molecular pharmaceutics, 4(4), 583-595 (2007-04-19)
This study measures the time-dependence of cellular caspase activation by anticancer drugs and compares it with that of cellular respiration. Intracellular caspase activation and cellular respiration were measured during continuous exposure of Jurkat, HL-60, and HL-60/MX2 (deficient in topoisomerase-II) cells
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