6-Fluoroindole is a halogen substituted indole. Experimental ionization potential of 6-fluoroindole has been evaluated. Preparation of 6-fluoroindole via nitration of indoline has been reported.

6-Fluoroindole may be used as reactant in the preparation of:

• tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• antibacterial agents
• antifungal agents
• Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the management of hyperglycemia in diabetes
• potent selective serotonin reuptake inhibitors
• inhibitors of HIV-1 attachment