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Merck
CN

74640

19-去甲睾酮

≥99.0% (HPLC)

别名:

17β-羟基-19-去甲雄甾-4-烯-3-酮, 17β-羟基-4-雌烯-3-酮, 19-去甲雄甾烯醇酮, 4-雌烯-17β-醇-3-酮, Nadrolone, 诺龙

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关于此项目

经验公式（希尔记法）:
C18H26O2
化学文摘社编号:
434-22-0
分子量:
274.40
UNSPSC Code:
51111800
NACRES:
NA.22
PubChem Substance ID:
57652521
EC Number:
207-101-0
Beilstein/REAXYS Number:
2055849
MDL number:
MFCD00003664
Assay:
≥99.0% (HPLC)
Form:
crystals

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InChI key

NPAGDVCDWIYMMC-IZPLOLCNSA-N

InChI

1S/C18H26O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-17,20H,2-9H2,1H3/t13-,14+,15+,16-,17-,18-/m0/s1

SMILES string

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@H]2O

assay

≥99.0% (HPLC)

form

crystals

optical activity

[α]20/D +57±2°, c = 1% in chloroform

drug control

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

functional group

hydroxyl, ketone

Quality Level

200

Gene Information

human ... SERPINA6(866), SHBG(6462)
rat ... Ar(24208), Nr3c2(25672), Pgr(25154)

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General description

19-Nortestosterone, also known as nandrolone or 17β-hydroxy-19-nor-4-androsten-3-one, is an androgenic anabolic steroid (AAS).

Application

19-Nortestosterone can be used as a reactant to prepare:
  • Fluorescent nandrolone-BODIPY conjugates to study intracellular localization and tracking of nandrolone using fluorescence microscope.
  • Optically pure hexadecahydrochrysene diastereomers, and chrysene enantiomers.

Other Notes

可能实行销售限制

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Carc. 2 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number
BCCN2901
BCCF3920
BCBP2063V
BCBJ1311V
BCBB6343V

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Simeon Pierre Fodouop Chegaing et al.
Steroids, 162, 108679-108679 (2020-06-23)
Although the discovery of antibiotics has decreased the spread and severity of infectious diseases, their uncontrolled use has lead to the emergence of bacterial resistance to existing chemotherapeutic agents. Bacterial disease thus remains a challenge for health authorities in worldwide
The use of symmetry in enantioselective synthesis: Four pairs of chrysene enantiomers prepared from 19-nortestosterone
Stastna E, et al.
Organic & Biomolecular Chemistry, 9(12), 4685-4694 (2011)
Synthesis and biological evaluation of nandrolone-bodipy conjugates
J Michal, et al.
Steroids, 97, 62-66 (2015)
P Kintz et al.
Journal of pharmaceutical and biomedical analysis, 24(5-6), 1125-1130 (2001-03-15)
A sensitive, specific and reproducible method for the quantitative determination of nandrolone in human hair has been developed. The sample preparation involved a decontamination step of the hair with methylene chloride. The hair sample (about 100 mg) was solubilized in
Pieter Van Renterghem et al.
Analytica chimica acta, 768, 41-48 (2013-03-12)
Due to their performance enhancing properties, use of anabolic steroids (e.g. testosterone, nandrolone, etc.) is banned in elite sports. Therefore, doping control laboratories accredited by the World Anti-Doping Agency (WADA) screen among others for these prohibited substances in urine. It
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