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Merck
CN

765449

官能化金纳米粒子COOH

5 nm diameter, carboxylic acid functionalized, PEG 5000 coated, dispersion in H2O

别名:

Au NP COOH, 金胶体

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关于此项目

UNSPSC Code:
12352302
NACRES:
NA.23
PubChem Substance ID:
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material

PEG 5000

form

dispersion in H2O, nanoparticles

packaging

glass bottle of 1 mL

OD

50

diameter

5 nm

pH

6.0-8.0 (25 °C)

solubility

water: miscible

density

1.00 g/cm3

λmax

515 nm

functional group

carboxylic acid

storage temp.

2-8°C

Application

功能化颗粒已被广泛用于研究纳米颗粒的细胞摄取和靶向药物递送。
Carboxylic acid functionalized, PEG 5000 coated and H2O dispersed gold nanoparticles (5 nm) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.

Features and Benefits

Decreases the cytotoxicity and increases efficiency of GNPs in targeted drug delivery. PEG increases the stability of the nanoparticles and prevents agglomeration.

Other Notes

  • form dispersion in H2O
  • OD 50
  • diameter 5 nm
  • storage temp. 2-8°C


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

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商品

The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.

Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

最近出现的许多高功能纳米材料为癌症的认识、诊断和治疗提供了新的方案。


Jennifer Mytych et al.
BioMed research international, 2015, 304575-304575 (2015-07-23)
Nanogold-based materials are promising candidate tools for nanobased medicine. Nevertheless, no conclusive information on their cytotoxicity is available. In the present study, we investigated the effects of gold nanoparticles (AuNPs) on human astrocytes in vitro. Nanogold treatment in a wide
Alexandre Albanese et al.
ACS nano, 5(7), 5478-5489 (2011-06-23)
Aggregation appears to be a ubiquitous phenomenon among all nanoparticles and its influence in mediating cellular uptake and interactions remain unclear. Here we developed a simple technique to produce transferrin-coated gold nanoparticle aggregates of different sizes and characterized their uptake
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 6, 2071-2071 (2020)



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货号GTIN
765449-1ML04061837524073