859095
Nα--乙酰基- L -赖氨酸甲酯 盐酸盐
98%
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关于此项目
线性分子式:
H2N(CH2)4CH(NHCOCH3)CO2CH3·HCl
化学文摘社编号:
分子量:
238.71
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
244-111-4
MDL number:
InChI
1S/C9H18N2O3.ClH/c1-7(12)11-8(9(13)14-2)5-3-4-6-10;/h8H,3-6,10H2,1-2H3,(H,11,12);1H/t8-;/m0./s1
InChI key
PCHGTXYLEAQWOM-QRPNPIFTSA-N
SMILES string
Cl.COC(=O)[C@H](CCCCN)NC(C)=O
assay
98%
form
powder
optical activity
[α]22/D −18°, c = 10 in 6 M HCl
reaction suitability
reaction type: solution phase peptide synthesis
mp
108-114 °C (lit.)
application(s)
peptide synthesis
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
H Nakayama et al.
Journal of immunological methods, 140(1), 119-125 (1991-06-24)
Antibodies directed against advanced glycosylation end products (AGEs) formed during a Maillard reaction have been generated and characterized. Since protein-bound AGEs recognized by the antibodies were labile to acid hydrolysis, the antibodies were further characterized by using the AGE-alpha-acetyl-L-lysine methyl
S J George et al.
Journal of vascular research, 38(5), 492-501 (2001-09-19)
The focus of this study was identification of the contribution of the plasminogen activator-plasmin system to smooth muscle cell proliferation and migration in human saphenous vein. Segments of human saphenous vein were grown in organ culture for up to 14
Xiaoyun Xu et al.
Journal of the American Chemical Society, 130(2), 703-709 (2007-12-18)
The reaction between N(alpha)-acetyllysine methyl ester (Lys) and 2'-deoxyguanosine (dGuo) was used to study structural aspects of DNA-protein cross-link (DPC) formation. The precise structure of DPCs depended on the nature of the oxidant and cross-linking reactions in which a series
P K Anonick et al.
Arteriosclerosis and thrombosis : a journal of vascular biology, 12(6), 708-716 (1992-06-01)
alpha-N-acetyl-L-lysine methyl ester (NALME) is a lysine analogue that reportedly binds to low-affinity lysine binding sites in plasmin(ogen) and miniplasmin(ogen). In the studies presented here, we show that NALME has antifibrinolytic activity; however, unlike the therapeutic agents epsilon-amino-n-caproic acid (epsilon
Sarah J George et al.
Journal of vascular research, 42(3), 247-254 (2005-05-05)
The effect of activation of endogenous transforming growth factor-beta (TGF-beta) on smooth muscle cell apoptosis was assessed in human saphenous vein. Segments of human saphenous vein, obtained at the time of bypass graft surgery, were cultured for 14 days. During
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