跳转至内容
Merck
CN

901906

2-二环己基膦基-2′,6′-二甲氧基联苯基

greener alternative

95%, powder or crystals

别名:

S Phos, SPhos

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C26H35O2P
化学文摘社编号:
657408-07-6
分子量:
410.53
NACRES:
NA.22
UNSPSC Code:
12161600
MDL number:
MFCD05861611

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

2-二环己基膦基-2′,6′-二甲氧基联苯基, 95%

InChI key

VNFWTIYUKDMAOP-UHFFFAOYSA-N

SMILES string

COc1cccc(OC)c1-c2ccccc2P(C3CCCCC3)C4CCCCC4

InChI

1S/C26H35O2P/c1-27-23-17-11-18-24(28-2)26(23)22-16-9-10-19-25(22)29(20-12-5-3-6-13-20)21-14-7-4-8-15-21/h9-11,16-21H,3-8,12-15H2,1-2H3

assay

95%

form

powder or crystals

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings
reagent type: ligand

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

164-166 °C (lit.)
165.5 °C

functional group

phosphine

greener alternative category

Aligned

正在寻找类似产品? 访问 产品对比指南

相关类别

Application

用于Suzuki-Miyaura偶联反应的高度通用配体； 芳基氯、受阻联芳基、杂联芳基。
SPhos may be used as a ligand in the following processes:
  • Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between Boc-protected aminomethyltrifluoroborate and aryl chlorides or hetaryl chlorides to form the corresponding aminomethylarenes.
  • Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between 4-methyl-substituted piperidinylzinc reagent and different aryl or heteroaryl iodides to form various substituted piperidines.
  • Intramolecular Suzuki-Miyaura coupling to form the 18-membered macrocyclic ring during the multi-step synthesis of riccardin C.
Utilized in conjunction with palladium to form a highly active catalyst for C-N bond formation

Legal Information

使用涉及的专利号：US 6307087；EP 1097158；JP 5758844；CA 2336691

General description

SPhos [2-Dicyclohexylphosphino-2′, 6′-dimethoxybiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. This product has been enhanced for catalysis. Click here for more information.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
WXBD5936V
WXBD0196V
WXBC7953V

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Highly diastereoselective arylations of substituted piperidines
Seel, Stephanie, et al.
Journal of the American Chemical Society, 133.13, 4774-4777 (2011)
Use of the SPhos Ligand to Suppress Racemization in Arylpinacolboronate Ester Suzuki Couplings Involving ?-Amino Acids. Synthesis of Biaryl Derivatives of 4-Hydroxyphenylglycine, Tyrosine, and Tryptophan
Prieto, Monica, et al.
The Journal of Organic Chemistry, 74.23, 9202-9205 (2009)
What makes for a good catalytic cycle? A theoretical study of the SPhos ligand in the Suzuki?Miyaura reaction
Kozuch, Sebastian, and Jan ML Martin
Chemical Communications (Cambridge, England), 47.17, 4935-4937 (2011)
Synthesis of 1, 5-disubstituted tetrazoles via Suzuki?Miyaura cross-coupling of 5-chloro-1-phenyltetrazole
Tang, Qing, and Ryan Gianatassio
Tetrahedron Letters, 51.27, 3473-3476 (2010)
Efficient synthesis of functionalized dibenzofurans by domino `twofold Heck/6?-electrocyclization?reactions of 2, 3-di-and 2, 3, 5-tribromobenzofuran
Hussain, Munawar, Nguyen Thai Hung, and Peter Langer
Tetrahedron Letters, 50.27, 3929-3932 (2009)
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持