910015
17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid
≥95%
别名:
Azido-PEG5-CH2CO2H, Azido-PEG5-acid, N3-PEG5-CH2COOH
方案
≥95%
表单
(Liquid or Semi-solid or Paste or Solid)
反应适用性
reaction type: click chemistry
reagent type: cross-linking reagent
官能团
azide
carboxylic acid
储存温度
2-8°C
SMILES字符串
OC(COCCOCCOCCOCCOCCN=[N+]=[N-])=O
应用
This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG5-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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