assay
≥95%
form
powder
reaction suitability
reagent type: linker
functional group
carboxylic acid, ester
storage temp.
2-8°C
Quality Level
Application
2,2,11-trimethyl-4-oxo-3,8-dioxa-5,11-diazatetradecan-14-oic acid is a heterobifunctional crosslinker useful for development of PROTAC degraders for targeted protein degradation or other bifunctional molecules in chemical biology. Incorporation of rigidity into the linker region may impact the 3D orientation of the molecules and thus ternary complex formation as well as optimization of drug-like properties. For linkers already conjugated to E3 ligase ligands, please visit our collection of Protein Degrader Building Blocks.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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