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线性分子式:
(C6H5)4As(Cl) · xH2O
化学文摘社编号:
分子量:
418.79 (anhydrous basis)
UNSPSC Code:
12161600
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-070-6
Beilstein/REAXYS Number:
3580063
MDL number:
InChI key
NGDWSDTZKCSLRK-UHFFFAOYSA-M
InChI
1S/C24H20As.ClH.H2O/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24;;/h1-20H;1H;1H2/q+1;;/p-1
SMILES string
O.[Cl-].c1ccc(cc1)[As+](c2ccccc2)(c3ccccc3)c4ccccc4
assay
97%
reaction suitability
core: arsenic, reagent type: catalyst
mp
258-260 °C (lit.)
Application
阳离子交换剂。用于制备砷酰胺、肟和碳水化合物衍生物。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
D Wolff et al.
Biochimica et biophysica acta, 688(1), 138-144 (1982-05-21)
In order to elucidate the mechanism of action of organochlorine insecticides on the ion transport in biological membranes, we have studied the effect of DDT and its analog DDE on the structural parameters of phosphatidylethanolamine (PE) planar bilayers. DDT and
Journal of the American Chemical Society, 114, 5130-5130 (1992)
S Manon et al.
Biochemistry and molecular biology international, 29(2), 375-385 (1993-02-01)
The effect of a group of non-usual inhibitors of ATP synthesis was investigated in yeast mitochondria. Tetraphenylphosphonium, tetraphenylarsonium and ethidium decreased the rate of ATP synthesis but did not decrease the ATP/O ratio. They did not inhibit the ATPase activity
A M George et al.
Archives of biochemistry and biophysics, 333(1), 66-74 (1996-09-01)
In this preliminary study, we report the cloning of the human MDR1 cDNA into a prokaryotic expression vector and the consequent functional expression of heterologous P-glycoprotein in Escherichia coli. We demonstrate increased resistance to the P-glycoprotein substrates TPA+, TPP+, and
P Gros et al.
Biochemistry, 31(7), 1992-1998 (1992-02-25)
The possibility that simple lipophilic cations such as tetraphenylphosphonium (TPA+), triphenylmethylphosphonium (TPMP+), and diphenyldimethylphosphonium (DDP+) are substrates for the multidrug-resistance transport protein, P-glycoprotein, was tested. Hamster cells transfected with and overexpressing mouse mdr1 or mouse mdr3 exhibit high levels of
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