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关于此项目
经验公式（希尔记法）:
C37H72O8PNa
化学文摘社编号:
分子量:
698.93
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
17:0 PA, 1,2-diheptadecanoyl-sn-glycero-3-phosphate (sodium salt), powder
SMILES string
[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCC)O
InChI
1S/C37H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36(38)43-33-35(34-44-46(40,41)42)45-37(39)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h35H,3-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/t35-;/m1./s1
InChI key
IAELRFKIVVBNTO-RUQJKXHKSA-M
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (830856P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 830856P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
Application
17:0 PA已用作BXD肝样品/脂质组学分析的内标和BXD血浆样品分析的内标。它可以用作内标混合物中的组分，以加标脑组织匀浆。
Biochem/physiol Actions
磷脂酸（PA）起脂质信使作用。它能增强肌肉蛋白的产生。PA也可以用作信号脂质。它在雷帕霉素（mTOR）信号转导的哺乳动物靶标中起关键作用。
General description
磷脂酸（PA）是磷脂池中的次要成分。它由两个脂肪酸和一个磷酸盐组成，并借助酯键与甘油分子共价连接。PA是细胞膜的重要组成部分。
Packaging
5 mL棕色玻璃螺旋盖小瓶（830856P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Sophie Ayciriex et al.
Frontiers in molecular neuroscience, 10, 211-211 (2017-07-27)
Impairment in cholesterol metabolism is associated with many neurodegenerative disorders including Alzheimer's disease (AD). However, the lipid alterations underlying neurodegeneration and the connection between altered cholesterol levels and AD remains not fully understood. We recently showed that cholesterol accumulation in
Yoshibumi Shimizu et al.
Prostaglandins & other lipid mediators, 150, 106450-106450 (2020-04-17)
Cyclic phosphatidic acid (cPA) is a lysophospholipid mediator that suppresses cancer metastasis and osteoarthritis. It also has neuroprotective roles in diseases such as multiple sclerosis and delayed neuronal death following transient ischemia. In order to take advantage of the properties
Pooja Jha et al.
Cell systems, 6(6), 722-733 (2018-06-18)
The genetics of individual lipid species and their relevance in disease is largely unresolved. We profiled a subset of storage, signaling, membrane, and mitochondrial liver lipids across 385 mice from 47 strains of the BXD mouse population fed chow or
Emily L Gill et al.
Journal of proteome research, 19(1), 424-431 (2019-11-13)
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain, as well as the degeneration of motor and nonmotor circuitries. The cause of neuronal death is currently unknown, although chronic
Guillermo Escalante et al.
Journal of the International Society of Sports Nutrition, 13, 24-24 (2016-06-09)
Phosphatidic acid (PA) is a lipid messenger that has been shown to increase muscle protein synthesis via signaling stimulation of the mammalian target of rapamycin (mTOR). MaxxTOR® (MT) is a supplement that contains PA as the main active ingredient but
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