form
powder
InChI
1S/C40H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-38(42)48-33-36(34-49-52(46,47)50-35-37(41)40(44)45)51-39(43)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h36-37H,3-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/t36-,37+;/m1./s1
InChI key
HNPCQASYRKKJRQ-JBEIVTSCSA-M
SMILES string
[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[Na+]
description
1,2-diheptadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt)
assay
>99% (TLC)
packaging
pkg of 1 × 10 mg (840028P-10mg), pkg of 1 × 25 mg (840028P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
General description
磷脂酰丝氨酸（PtdSer）是阴离子磷脂，大量存在于真核细胞内。10%的总细胞脂质由磷脂酰丝氨酸组成。O-磷酸-L-丝氨酸是对热稳定的底物。
Application
17：0 Ps用作内标，用于BXD肝脏和血浆样品分析。 也可作为标准品，通过液相色谱-串联质谱，评估酿酒酵母细胞脂质组。
Biochem/physiol Actions
磷脂酰丝氨酸（PtdSer）参与细胞内各种信号通路。同时在细胞凋亡和血液凝结中起主要作用。
Packaging
5 mL棕色玻璃螺旋盖样品瓶（840028P-10mg）
5 mL棕色玻璃螺旋盖样品瓶（840028P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Karamat Mohammad et al.
Journal of visualized experiments : JoVE, (157) (2020-03-24)
Lipids are structurally diverse amphipathic molecules that are insoluble in water. Lipids are essential contributors to the organization and function of biological membranes, energy storage and production, cellular signaling, vesicular transport of proteins, organelle biogenesis, and regulated cell death. Because
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
Emily L Gill et al.
Journal of proteome research, 19(1), 424-431 (2019-11-13)
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain, as well as the degeneration of motor and nonmotor circuitries. The cause of neuronal death is currently unknown, although chronic
Rose M Gathungu et al.
Analytical chemistry, 90(22), 13523-13532 (2018-09-29)
Lipidomics requires the accurate annotation of lipids in complex samples to enable determination of their biological relevance. We demonstrate that unintentional in-source fragmentation (ISF, common in lipidomics) generates ions that have identical masses to other lipids. Lysophosphatidylcholines (LPC), for example
Jason G Kay et al.
Cell communication and signaling : CCS, 17(1), 126-126 (2019-10-17)
Phosphatidylserine (PtdSer), an essential constituent of eukaryotic membranes, is the most abundant anionic phospholipid in the eukaryotic cell accounting for up to 10% of the total cellular lipid. Much of what is known about PtdSer is the role exofacial PtdSer
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