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Merck
CN

850365C

Avanti

18:0 PC (DSPC)

Avanti Research™ - A Croda Brand

别名:

1,2-dioctadecanoyl-sn-glycero-3-phosphocholine; DSPC; PC(18:0/18:0)

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关于此项目

经验公式（希尔记法）:
C44H88NO8P
CAS Number:
816-94-4
分子量:
790.15
MDL编号:
MFCD00036905
UNSPSC代码:
51191904
NACRES:
NA.25

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描述

1,2-distearoyl-sn-glycero-3-phosphocholine, chloroform

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (850365C-25mg)
pkg of 1 × 20 mL (850365C-500mg)
pkg of 2 × 20 mL (850365C-1g)
pkg of 2 × 4 mL (850365C-200mg)

制造商/商品名称

Avanti Research™ - A Croda Brand

浓度

10 mg/mL (850365C-25mg)
25 mg/mL (850365C-1g)
25 mg/mL (850365C-200mg)
25 mg/mL (850365C-500mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChI key

NRJAVPSFFCBXDT-HUESYALOSA-N

相关类别

一般描述

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

应用

18:0 PC (DSPC) has been used in the preparation of microbubbles (MBs). It is suitable for use in the synthesis of methylene blue (MB)-liposome synthesis and in the preparation of unilamellar vesicles

生化/生理作用

18:0 PC (DSPC) liposomes/1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, along with Rhamnolipids (RLs) can serve as the best combination for drug delivery application. It can help to maintain the stability of curcumin.

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850365C-1g)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850365C-500mg)
5 mL Clear Glass Sealed Ampule (850365C-200mg)
5 mL Clear Glass Sealed Ampule (850365C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品（2类）
危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Interaction of curcumin with 1, 2-dioctadecanoyl-sn-glycero-3-phosphocholine liposomes: Intercalation of rhamnolipids enhances membrane fluidity, permeability and stability of drug molecule
Moussa Z, et al.
Colloids and Surfaces. B, Biointerfaces, 149, 30-37 (2017)
In vivo transfection and detection of gene expression of stem cells preloaded with DNA-carrying microbubbles
Tavri S, et al.
Radiology, 276(2), 518-525 (2015)
Methylene-Blue-Encapsulated Liposomes as Photodynamic Therapy Nano Agents for Breast Cancer Cells
Wu PT, et al.
Nanomaterials, 9(1), 14-14 (2019)
Ana Reis et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183133-183133 (2019-12-01)
Food polyphenols in fruits juices, tea, coffee, wine and beer confer sensory properties such as colour, astringency and bitterness. The development of functional healthy drinks without the unpleasant sensory feeling is boosting research for a clearer understanding on the interactions
Joshua Owen et al.
Langmuir : the ACS journal of surfaces and colloids, 35(31), 10014-10024 (2018-11-30)
Phospholipid coated microbubbles are currently in widespread clinical use as ultrasound contrast agents and under investigation for therapeutic applications. Previous studies have demonstrated the importance of the coating nanostructure in determining microbubble stability and its dependence upon both composition and
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