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文件

安全信息

850464C

Avanti

18:0-14:0 PC

1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine, chloroform

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别名:
1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine; SMPC; PC(18:0/14:0)
经验公式（希尔记法）:
C40H80NO8P
CAS号:
206640-20-2
分子量:
734.04
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 2.5 mL (850464C-25mg)

manufacturer/tradename

Avanti Polar Lipids 850464C

浓度

10 mg/mL (850464C-25mg)

lipid type

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

一般描述

Phosphatidylcholine (PC) is a major bilayer-forming phospholipid in which the headgroup carries a positively and negatively charged quaternary amine and a phosphate, respectively.

应用

18:0-14:0 PC (1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine) may be used in liposomes to study its interference in the proliferation of several cell lines using transmission electron microscopy (TEM).

生化/生理作用

Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.

包装

5 mL Clear Glass Sealed Ampule (850464C-25mg)

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Anna Werlein et al.
Biochimica et biophysica acta, 1848(7), 1599-1608 (2015-04-29)
According to early experiments with natural extracts, phosphatidylcholines (PCs) are widely considered essentially non-toxic. In addition to these physiological mixed-chain PCs, many different synthetic diacyl-PCs are currently available, but they have never been systematically evaluated for any interference with cell
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features

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