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文件

860585P

Avanti

17:0 SM (d18:1/17:0)

Name: 17:0 SM (d18:1/17:0)
Brand: AVANTI

Avanti Polar Lipids 860585P, powder

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别名:

N-十七酰-D-赤-鞘氨醇磷酸胆碱

经验公式（希尔记法）:

C₄₀H₈₁N₂O₆P

CAS号:

121999-64-2

分子量:

717.05

NACRES:

NA.25

形式

powder

包装

pkg of 1 × 10 mg (860585P-10mg)
pkg of 1 × 5 mg (860585P-5mg)

制造商/商品名称

Avanti Polar Lipids 860585P

脂质类型

sphingolipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C40H81N2O6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-40(44)41-38(37-48-49(45,46)47-36-35-42(3,4)5)39(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h31,33,38-39,43H,6-30,32,34-37H2,1-5H3,(H-,41,44,45,46)/b33-31+/t38-,39+/m0/s1

InChI key

YMQZQHIESOAPQH-JXGHDCMNSA-N

应用

N-十七烷酰-D-赤型-神经鞘氨醇磷酸胆碱 (17:0 SM (d18:1/17:0)) 可作为质谱法 (MS) 定量分析C17-鞘磷脂 (SM) 的内标。它可作为液相色谱-质谱 (LC-MS) 法定量检测血清和骨骼肌中脂质的内标。它还可作为校准保留时间以及用甲醇和甲基叔丁基醚提取血样中脂质的内标。

包装

5 mL棕色玻璃螺旋盖小瓶(860585P-10mg)

5 mL棕色玻璃螺旋盖小瓶(860585P-5mg)

通常也和此产品一起购买

产品编号

说明

价格

储存分类代码

11 - Combustible Solids

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Deep Profiling of Immunosuppressive Glycosphingolipids and Sphingomyelins in Wild Cordyceps.

Jianing Mi et al.

Journal of agricultural and food chemistry, 66(34), 8991-8998 (2018-07-31)

Deep profiling of glycosphingolipids and sphingomyelins in wild Cordyceps was carried out by using offline chromatographic enrichment followed by ultrahigh performance liquid chromatography-ultrahigh definition-quadrupole time-of-flight mass spectrometry (UHPLC-UHD-Q-TOF-MS). A total of 119 glycosphingolipids (72 new ones) and 87 sphingomyelins (43

Long-term use of fluoxetine accelerates bone loss through the disruption of sphingolipids metabolism in bone marrow adipose tissue.

Huili Zhang et al.

Translational psychiatry, 10(1), 138-138 (2020-05-14)

Fluoxetine is a commonly prescribed antidepressant, and the mechanisms of increased bone fragility with its long-term use remain largely unknown. Here, we show that long-term administration of fluoxetine induces the disruption of sphingolipids metabolism in bone marrow adipose tissue (BMAT)through

Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort.

Dinesh Kumar Barupal et al.

Scientific data, 5, 180263-180263 (2018-11-21)

Alzheimer's disease (AD) is a major public health priority with a large socioeconomic burden and complex etiology. The Alzheimer Disease Metabolomics Consortium (ADMC) and the Alzheimer Disease Neuroimaging Initiative (ADNI) aim to gain new biological insights in the disease etiology.

Interventional effects of the direct application of "Sanse powder" on knee osteoarthritis in rats as determined from lipidomics via UPLC-Q-Exactive Orbitrap MS.

Peng Wu et al.

Chinese medicine, 15, 9-9 (2020-01-31)

Our previous clinical evidence suggested that the direct application of "Sanse powder" the main ingredient of "Yiceng" might represent an alternative treatment for knee osteoarthritis. However, the mechanism underlying its effect is poorly understood. In this study, we investigated the

Discovery and characterization of selective human sphingomyelin synthase 2 inhibitors.

Ryutaro Adachi et al.

European journal of medicinal chemistry, 136, 283-293 (2017-05-16)

Sphingomyelin synthase (SMS) is a membrane enzyme that catalyzes the synthesis of sphingomyelin, is required for the maintenance of plasma membrane microdomain fluidity, and has two isoforms: SMS1 and SMS2. Although these isoforms exhibit the same SMS activity, they are

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