A-916
7-氨基氯硝西泮标准液 溶液
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
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关于此项目
经验公式（希尔记法）:
C15H12ClN3O
化学文摘社编号:
分子量:
285.73
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
certified reference material
Quality Level
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
2-8°C
SMILES string
NC1=CC=C2C(C(C3=C(Cl)C=CC=C3)=NCC(N2)=O)=C1
InChI
1S/C15H12ClN3O/c16-12-4-2-1-3-10(12)15-11-7-9(17)5-6-13(11)19-14(20)8-18-15/h1-7H,8,17H2,(H,19,20)
InChI key
HEFRPWRJTGLSSV-UHFFFAOYSA-N
General description
该认证的Snap-N-Spike®溶液，适合作为法医分析、临床毒理学和尿液药物检测的许多GC/MS或LC/MS应用中校准物或对照品中的起始材料。作为主要代谢产物，7-氨基氯硝西泮可用于监测母体药物氯硝西泮的使用。以Klonopin®和Rivotril出售的氯硝西泮是一种长效苯二氮卓类药物，具有抗焦虑、抗惊厥、肌肉松弛和催眠作用。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Klonopin is a registered trademark of Hoffmann-La Roche Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
35.6 °F - closed cup
flash_point_c
2 °C - closed cup
法规信息
危险化学品
此项目有
Marjorie Chèze et al.
Forensic science international, 145(2-3), 123-130 (2004-09-29)
The number of reports on drug facilitated crimes is increasing these last years. Apart from ethanol and cannabis, benzodiazepines (BZD) and analogs are the most common drugs reported to be used probably due to their amnesic and sedative properties. We
Simple high-performance liquid chromatographic assay for the routine monitoring of clonazepam in plasma.
R L Heazlewood et al.
Journal of chromatography, 336(1), 229-233 (1984-12-07)
D R Peng et al.
Pediatric pharmacology (New York, N.Y.), 4(3), 155-159 (1984-01-01)
The N-acetylation of the reduced metabolite of clonazepam 7-amino-clonazepam was studied in cytosolic preparation from human fetal and adult livers. The metabolite formed 7-acetamido-clonazepam was measured with high performance liquid chromatography. A bimodal distribution of the N-acetyltransferase activities was observed
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