grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
clinical testing
pharmaceutical (small molecule)
format
single component solution
storage temp.
−20°C
SMILES string
[2H]C([2H])([2H])C(C(O)=O)C(O)=O
InChI
1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)/i1D3
InChI key
ZIYVHBGGAOATLY-FIBGUPNXSA-N
General description
甲基丙二酸是一种丙二酸衍生物，是脂肪和蛋白质代谢中至关重要的中间体，在能量代谢中起关键作用。甲基丙二酸水平升高可由导致甲基丙二酸尿症的先天性代谢缺陷引起或表明早期维生素B<sub>12</sub>缺乏症。该内标物适用于在新生儿筛查和临床检测应用中通过LC/MS或GC/MS定量甲基丙二酸水平，以检测甲基丙二酸血症和诊断维生素B<sub>12</sub>缺乏症。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
35.6 °F - closed cup
flash_point_c
2 °C - closed cup
法规信息
美国出口管控产品
危险化学品
此项目有
Patrick J O'Hern et al.
eLife, 6 (2017-05-04)
Spinal Muscular Atrophy (SMA) is caused by diminished Survival of Motor Neuron (SMN) protein, leading to neuromuscular junction (NMJ) dysfunction and spinal motor neuron (MN) loss. Here, we report that reduced SMN function impacts the action of a pertinent microRNA
Laura Nadal et al.
Frontiers in aging neuroscience, 9, 24-24 (2017-02-24)
The development of the nervous system involves the overproduction of synapses but connectivity is refined by Hebbian activity-dependent axonal competition. The newborn skeletal muscle fibers are polyinnervated but, at the end of the competition process, some days later, become innervated
Alessandra Lo Cicero et al.
Scientific reports, 6, 34798-34798 (2016-10-16)
Hutchinson-Gilford progeria syndrome (HGPS) is a rare fatal genetic disorder that causes systemic accelerated aging in children. Thanks to the pluripotency and self-renewal properties of induced pluripotent stem cells (iPSC), HGPS iPSC-based modeling opens up the possibility of access to
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M-105-1ML | 04061833976753 |
| Z566012-12EA | 04061832350875 |
| 25358 | 04061833660140 |