E-081
依替唑仑标准液 CRM 溶液
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
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关于此项目
经验公式（希尔记法）:
C17H15ClN4S
化学文摘社编号:
分子量:
342.85
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
certified reference material
质量水平
表单
liquid
特点
(Snap-N-Spike®)
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
drug control
Narcotic Licence Schedule B (Switzerland); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
浓度
1.0 mg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
包装形式
single component solution
储存温度
−20°C
SMILES字符串
CCC1=CC2=C(S1)N3C(CN=C2C4=CC=CC=C4Cl)=NN=C3C
InChI
1S/C17H15ClN4S/c1-3-11-8-13-16(12-6-4-5-7-14(12)18)19-9-15-21-20-10(2)22(15)17(13)23-11/h4-8H,3,9H2,1-2H3
InChI key
VMZUTJCNQWMAGF-UHFFFAOYSA-N
一般描述
经认证的溶液标准，可用于临床毒理学、尿液药物测试或法医分析中的LC/MS或GC/MS苯二氮卓测试方法。依替唑仑，商品名为Etilaam、Etizola或Depas，是一种苯二氮卓类似物，可用于失眠、焦虑或惊恐发作的短期治疗。依替唑仑也被作为化合致幻药销售，在欧洲和美国都有药物滥用的案例。
生化/生理作用
依替唑仑是一种噻吩并二氮杂卓抗焦虑药，与其他苯二氮卓类药物相比具有较低的依赖性。它与其他苯并二氮杂卓类药物的不同之处在于其分子具有噻吩环而不是苯环。它具有抗惊厥、镇静、抗焦虑、遗忘、催眠和肌肉松弛作用。它是通过作用于苯二氮卓受体而发挥作用的。它被用于治疗失眠、中度抑郁和社交焦虑症，并偶尔用于治疗眼睑痉挛和皮肤病变。
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
49.5 °F
闪点(°C)
9.7 °C
法规信息
监管及禁止进口产品
此项目有
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Masahiro Hirase et al.
European journal of pharmacology, 597(1-3), 46-50 (2008-09-16)
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 31(4), 739-750 (2005-08-27)
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