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Merck
CN

N-031

去甲芬太尼标准液 草酸酯 溶液

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式(希尔记法):
C14H20N2O · C2H2O4
化学文摘社编号:
分子量:
322.36
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级

certified reference material

质量水平

表单

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland)

浓度

1.0 mg/mL in methanol (as free base)

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

包装形式

single component solution

储存温度

−20°C

SMILES字符串

OC(=O)C(O)=O.CCC(=O)N(C1CCNCC1)c2ccccc2

InChI

1S/C14H20N2O.C2H2O4/c1-2-14(17)16(12-6-4-3-5-7-12)13-8-10-15-11-9-13;3-1(4)2(5)6/h3-7,13,15H,2,8-11H2,1H3;(H,3,4)(H,5,6)

InChI key

OLFNESLXXQCODF-UHFFFAOYSA-N

一般描述

去甲芬太尼是芬太尼的主要尿代谢产物,芬太尼是一种有效的合成镇痛药,以各种商品名出售,包括Sublimaze、Duragesic®、Actiq®和Fentora®。 这种经认证的加标溶液®适用于从临床毒理学和法医分析到尿液药物检验和疼痛处方监测的众多GC/MS或LC/MS检验应用。

法律信息

Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Resp. Sens. 1 - STOT SE 1

靶器官

Eyes,Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

危险化学品
易制毒化学品(2类)
此项目有

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D E Feierman
Anesthesia and analgesia, 82(5), 936-941 (1996-05-01)
The metabolism of fentanyl was investigated using rat liver microsomes to determine whether fentanyl is metabolized by rat liver microsomal cytochrome P450 and, if so, which isoform is responsible for the metabolism. Microsomes isolated from rats pretreated with phenobarbital were
Nadine F J Van Nimmen et al.
Journal of clinical pharmacology, 50(6), 667-678 (2010-01-26)
Delivery rates and plasma concentrations vary among patients treated with fentanyl patches. Absorption and urinary excretion characteristics of fentanyl were studied in patients undergoing palliative care. Almost 500 patches were analyzed for residual fentanyl content. Fentanyl and norfentanyl levels were
Alphonse Poklis et al.
Journal of analytical toxicology, 28(6), 422-425 (2004-11-02)
A study of the urinary concentration of fentanyl (F) and its major metabolite norfentanyl (NF) in chronic pain patients treated with the Duragesic continuous release transdermal patches is presented. These patches are available in 10, 20, 30, and 40 cm(2)
Henry J Carson et al.
Legal medicine (Tokyo, Japan), 12(3), 157-159 (2010-04-07)
We recently encountered a subject who died from an uncommon misuse of a fentanyl transdermal patch, chewing, followed by complications of aspiration of the patch. We report this case to alert medical examiners to the troubling trend of increased fentanyl
Vera Coopman et al.
Forensic science international, 169(2-3), 223-227 (2006-05-03)
Fentanyl is a potent synthetic narcotic analgesic administered in the form of a transdermal patch for the management of chronic pain. A 78-year-old woman with a history of cancer was found dead in bed. She was lying on her back.

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