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经验公式(希尔记法):
C14H20N2O · C2H2O4
化学文摘社编号:
分子量:
322.36
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
InChI
1S/C14H20N2O.C2H2O4/c1-2-14(17)16(12-6-4-3-5-7-12)13-8-10-15-11-9-13;3-1(4)2(5)6/h3-7,13,15H,2,8-11H2,1H3;(H,3,4)(H,5,6)
InChI key
OLFNESLXXQCODF-UHFFFAOYSA-N
SMILES string
OC(=O)C(O)=O.CCC(=O)N(C1CCNCC1)c2ccccc2
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
drug control
Narcotic Licence Schedule A (Switzerland)
concentration
1.0 mg/mL in methanol (as free base)
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
storage temp.
−20°C
Quality Level
General description
去甲芬太尼是芬太尼的主要尿代谢产物,芬太尼是一种有效的合成镇痛药,以各种商品名出售,包括Sublimaze、Duragesic®、Actiq®和Fentora®。 这种经认证的加标溶液®适用于从临床毒理学和法医分析到尿液药物检验和疼痛处方监测的众多GC/MS或LC/MS检验应用。
Legal Information
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Resp. Sens. 1 - STOT SE 1
target_organs
Eyes,Central nervous system
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
危险化学品
易制毒化学品(2类)
此项目有
Stephanie Oechsler et al.
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Mindy J Hull et al.
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Fatalities associated with fentanyl hydrochloride are increasingly seen in Massachusetts. Between September 2005 and November 2006, 5009 medicolegal investigations associated 107 deaths with licit or illicit fentanyl use, along with a co-detection of an opiate/opioid or cocaine/benzoylecognine, or both. Deaths
Teijo I Saari et al.
European journal of clinical pharmacology, 64(1), 25-30 (2007-11-08)
Fentanyl is a widely used opioid analgesic, which is extensively metabolized by hepatic cytochrome P450 (CYP) 3A. Recent reports suggest that concomitant administration of CYP3A inhibitors with fentanyl may lead to dangerous drug interactions. The potential interactions of fentanyl with
D E Feierman
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The metabolism of fentanyl was investigated using rat liver microsomes to determine whether fentanyl is metabolized by rat liver microsomal cytochrome P450 and, if so, which isoform is responsible for the metabolism. Microsomes isolated from rats pretreated with phenobarbital were
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