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Merck
CN

Z-003

左匹克隆标准液 溶液

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式(希尔记法):
C17H17ClN6O3
化学文摘社编号:
分子量:
388.81
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-835-2
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产品名称

左匹克隆标准液 溶液, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

InChI key

GBBSUAFBMRNDJC-UHFFFAOYSA-O

InChI

1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/p+1

SMILES string

C[NH+]1CCN(CC1)C(=O)OC2N(C(=O)c3nccnc23)c4ccc(Cl)cn4

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

General description

经过认证的溶液标准,适用于临床毒理学、法医分析、药学研究或尿液药物测试的LC/MS或GC/MS应用中。  佐匹克隆是一种非苯二氮卓类催眠药,商品名为Imovane®和ZImovane®,处方用于治疗失眠。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Imovane is a registered trademark of Sanofi-Aventis
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

法规信息

监管及禁止进口产品
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Judith Peacey et al.
The Journal of nervous and mental disease, 200(1), 83-87 (2012-01-03)
Adult patients (N = 100) being treated for acute psychiatric illness were interviewed about their sleep problems and attitudes toward available treatments. Most (74%) were using at least one prescribed psychotropic drug with hypnotic or sedative effects. Participants prescribed three
[Determination of zopiclone in serum by gas chromatographic method].
Zi-ru Cheng et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 30(4), 314-315 (2012-07-19)
Julia Boyle et al.
Journal of clinical psychopharmacology, 32(5), 704-709 (2012-08-29)
Next-day residual effects of single evening doses of 3 mg of eszopiclone, 7.5 mg of zopiclone, and placebo were assessed in a randomized, double-blind, placebo-controlled, 3-way crossover study that used a mild sleep restriction protocol (sleep duration, 7 hours). During
Milena Araújo Tonon et al.
Analytical and bioanalytical chemistry, 405(1), 267-273 (2012-11-07)
A new high-performance liquid chromatographic method with triple quadrupole mass spectrometry detection was developed and validated for the quantification of zopiclone enantiomers in rat brain samples. Zopiclone enantiomers were resolved on a CHIRALPAK AD column with a mobile phase consisting
Alan Wayne Jones et al.
Forensic science international, 222(1-3), 118-123 (2012-06-08)
The concentrations of zolpidem and zopiclone were determined in peripheral blood samples in two forensic materials collected over a 10-year period (2001-2010). The z-hypnotics were determined in venous blood from living subjects (impaired drivers) and in femoral blood from deceased

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