05-827
Anti-Glucocorticoid Receptor Antibody, clone FIGR
clone FIGR, Upstate®, from mouse
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
FIGR, monoclonal
Application:
IP, WB
Citations:
6
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
FIGR, monoclonal
Gene Information
human ... NR3C1(2908)
species reactivity
hamster, mouse, rat
should not react with
human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
General description
85-100kDa
Immunogen
Native glucocorticoid receptor purified from rat liver
Application
Detect Glucocorticoid Receptor with Anti-Glucocorticoid Receptor Antibody, clone FIGR (Mouse Monoclonal Antibody), that has been shown to work in IP & WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
Biochem/physiol Actions
glucocorticoid receptor
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Purified
Preparation Note
2 years at -20°C
Analysis Note
routinely evaluated by immunoblot on RIPA lysates from L6, PC12, and 3T3/A31 cells.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
J Richardson et al.
Molecular endocrinology (Baltimore, Md.), 13(4), 546-554 (1999-04-09)
The glutamate synthetase gene (GS) contains a composite glucocorticoid response element (cGRE) comprised of a GRE and an adjacent element with features of both a cAMP-response element (CRE) and a 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE). The CRE/TRE element of
Arman Nayebosadri et al.
American journal of physiology. Cell physiology, 305(3), C309-C322 (2013-05-25)
The lamina serves to maintain the nuclear structure and stiffness while acting as a scaffold for heterochromatin and many transcriptional proteins. Its role in endothelial mechanotransduction, specifically how nuclear mechanics impact gene regulation under shear stress, is not fully understood.
J E Bodwell et al.
The Journal of biological chemistry, 266(12), 7549-7555 (1991-04-25)
Glucocorticoid receptors in vivo are phosphorylated in the absence of hormone and become hyperphosphorylated in the presence of glucocorticoid agonist but not antagonists (Ortí, E., Mendel, D.B., Smith, L.I., and Munck, A. (1989) J. Biol. Chem. 264, 9728-9731). As a
R C Kaltreider et al.
Environmental health perspectives, 109(3), 245-251 (2001-05-03)
Chronic human exposure to nonovertly toxic doses of arsenic is associated with an increased risk of cancer. Although its carcinogenic mechanism is still unknown, arsenic does not directly cause DNA damage or mutations and is therefore thought to act principally
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