The best-in-class solution for nucleic acid removal at high salt concentration in Bioprocessing

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The Benzonase^® Salt Tolerant endonuclease Emprove^® Expert is a new enzyme, different in amino acids sequence from other Benzonase^® endonuclease references. It was designed with state-of-the-art protein engineering capabilities, to ensure the highest activity at high salt concentrations. The protein is a monomer with a molecular weight of about 27 kDa . The protein has an isoelectric point (pI) at pH 9.68. It is functional between pH 6 and 10, and from 0 °C to above 37 °C. Mg2+ (1–2 mM) is required for enzyme activity.

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany