Merck
CN

1.24069

SAFC

碳酸钙

EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, E170, FCC

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别名:
Calcium carbonate
线性分子式:
CaCO3
CAS号:
分子量:
100.09
Beilstein:
8008338
MDL编号:
E编号:
E170
EC索引号:
207-439-9

等级

GMO free
Halal
Kosher
cGMP

质量水平

Agency

BP
Ph. Eur.
USP

reg. compliance

FCC

产品线

EMPROVE® ESSENTIAL

形式

powder

密度

2.93 g/mL at 25 °C (lit.)

application(s)

pharmaceutical
solid formulation

异质活性

Aflatoxin

储存温度

2-30°C

SMILES string

[Ca++].[O-]C([O-])=O

InChI

1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2

InChI key

VTYYLEPIZMXCLO-UHFFFAOYSA-L

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一般描述

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Due to regulatory developments, there is an increasing interest in titanium dioxide-free solutions for the coloring of solid dosage forms. Parteck® TA - our titanium dioxide alternative - is a mineral and nature-identical pigment specifically developed for the use in tablet film coatings. It helps to achieve a level of covering and whiteness comparable to titanium dioxide film coatings without affecting your tablets’ performance. The enhanced opacity is ensured by its unique morphology and designed particle size distribution

特点和优势

  • A mineral, nature-identical pigment
  • Excellent compatibility with HPMC and PVA film coatings (including our PARTECK® COAT excipient)
  • High process efficiency due to lower viscosity of spraying liquids
  • Enables an appealing and uniform tablet appearance
  • Enhanced opacity due to tailored particle size distribution and unique morphology

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

13 - Non Combustible Solids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

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商品

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

相关内容

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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