8.51061
2-Chlorotrityl chloride
Novabiochem®
别名:
2-Chlorotrityl chloride
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关于此项目
经验公式(希尔记法):
C19H14Cl2
CAS Number:
分子量:
313.22
MDL编号:
UNSPSC代码:
12352107
EC索引号:
255-647-3
NACRES:
NA.22
质量水平
产品线
Novabiochem®
方案
≥95.0% (HPLC)
表单
powder
制造商/商品名称
Novabiochem®
mp
133.0-137.0 °C
应用
peptide synthesis
储存温度
2-30°C
SMILES字符串
ClC(c3c(cccc3)Cl)(c2ccccc2)c1ccccc1
InChI
1S/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H
InChI key
JFLSOKIMYBSASW-UHFFFAOYSA-N
一般描述
Hyperacid-labile ester protecting group [1]. Introduced under extremely mild conditions by reacting together the acid, trityl chloride and DIPEA in DCM. Ideal for the protection of the C-terminal carboxylic acid group of C-terminal protected peptide fragments, monoprotection of diacids and as a general carboxylic acid protecting group in organic synthesis.
Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS
Literature references
[1] P. Athanassopoulos, et al. (1995) Tetrahedron Lett., 36, 5645.
Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS
Literature references
[1] P. Athanassopoulos, et al. (1995) Tetrahedron Lett., 36, 5645.
分析说明
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 133 °C
Melting range (upper value): ≤ 137 °C
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 133 °C
Melting range (upper value): ≤ 137 °C
Assay (HPLC, area%): ≥ 95.0 % (a/a)
其他说明
Replaces: 01-63-0045
法律信息
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Warning
危险分类
Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
8A - Combustible, corrosive hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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