AB1832P
抗白介素-1β 抗体
Chemicon®, from rabbit
别名:
IL-1beta
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
neutralization
western blot
neutralization
western blot
Species reactivity:
rat
Citations:
29
Technique(s):
ELISA: suitable
neutralization: suitable
western blot: suitable
neutralization: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗白介素-1β 抗体, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
neutralization: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Il1B(24494)
Application
ELISA：0.5 μg/mL，当使用大鼠TNF-1包被板时，稀释液将允许
0.2-0.4 ng/孔的检测（直接ELISA）。
蛋白质印迹：0.1-0.2 μg/mL，在还原或非还原条件下，该稀释液应提供1.5-3.0 ng/泳道的检测限。
中和：为了产生对大鼠IL-1β（0.2 ng/mL）生物活性的½最大抑制（ND50），需要0.09-0.14 μg/mL的抗体浓度。
最终工作稀释度必须由最终使用者进行确定。
0.2-0.4 ng/孔的检测（直接ELISA）。
蛋白质印迹：0.1-0.2 μg/mL，在还原或非还原条件下，该稀释液应提供1.5-3.0 ng/泳道的检测限。
中和：为了产生对大鼠IL-1β（0.2 ng/mL）生物活性的½最大抑制（ND50），需要0.09-0.14 μg/mL的抗体浓度。
最终工作稀释度必须由最终使用者进行确定。
抗白细胞介素-1β抗体是针对白细胞介素-1β的抗体，可用于ELISA、WB、NEUT。
研究子类别
细胞因子&细胞因子受体
细胞因子&细胞因子受体
研究类别
炎症 & 免疫学
炎症 & 免疫学
Biochem/physiol Actions
与大鼠白细胞介素-1β（IL-1β）反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
高纯度（>98%）重组大鼠IL-1β。
Other Notes
替代品：04-462；MABF22
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
亲和纯化的免疫球蛋白。 从0.5X PBS pH 7.4中冻干，不含防腐剂。 用无菌蒸馏水复溶。
Preparation Note
保持冻干物料干燥至低于0°C。复溶后，以方便的未稀释等分试样在-20°C下保存长达6个月。应避免反复冻/融循环。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Elina Mäkinen et al.
Brain, behavior, and immunity, 97, 250-259 (2021-07-06)
Increasing evidence shows obesity and poor metabolic health are associated with cognitive deficits, but the mechanistic connections have yet to be resolved. We studied rats selectively bred for low and high intrinsic aerobic capacity in order to test the association
Xiaonan Zhuang et al.
Journal of cellular and molecular medicine, 25(1), 147-160 (2020-11-19)
We investigated how Src-homology 2-domain phosphatase-1 (SHP-1) regulates the inflammatory response in endotoxin-induced uveitis (EIU), and the signalling pathways involved. One week after intravitreal injection of short hairpin RNA targeting SHP-1 or SHP-1 overexpression lentivirus in rats, we induced ocular
Erika Hernández-Aquino et al.
World journal of gastroenterology, 23(24), 4354-4368 (2017-07-15)
To study the molecular mechanisms involved in the hepatoprotective effects of naringenin (NAR) on carbon tetrachloride (CCl4)-induced liver fibrosis. Thirty-two male Wistar rats (120-150 g) were randomly divided into four groups: (1) a control group (n = 8) that received
Qiong Cao et al.
PloS one, 12(10), e0186764-e0186764 (2017-10-20)
Microglia activation and associated inflammatory response are involved in the pathogenesis of different neurodegenerative diseases. We have reported that Notch-1 and NF-κB/p65 signalling pathways operate in synergy in regulating the production of proinflammatory mediators in activated microglia. In the latter
A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.
Cavailles, P; Flori, P; Papapietro, O; Bisanz, C; Lagrange, D; Pilloux, L; Massera et al.
PLoS Pathogens null
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