MAB1273C3
抗线粒体抗体，克隆 113-1，Cy3偶联物
clone 113-1, from mouse, CY3 conjugate
别名:
Human Mitochondria
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
CY3 conjugate
Clone:
113-1, monoclonal
Application:
immunocytochemistry
Species reactivity:
human (mitochondria protein)
Citations:
7
Technique(s):
immunocytochemistry: suitable
产品名称
抗线粒体抗体，克隆 113-1，Cy3偶联物, clone 113-1, from mouse, CY3 conjugate
biological source
mouse
conjugate
CY3 conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
113-1, monoclonal
species reactivity
human (mitochondria protein)
should not react with
rat (mitochondria protein), mouse (mitochondria protein)
technique(s)
immunocytochemistry: suitable
isotype
IgG1
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
计算值为60 kDa
该抗体可识别人细胞中线粒体的60 kDa非糖基化蛋白组分。它可用于染色细胞、组织或生化制剂中的线粒体，并可用作亚细胞组分中线粒体的标志物。MAB1273C3通过免疫沉淀识别65 kD的蛋白，并在人细胞的细胞质中产生条状的“意大利面条状”染色模式。
Analysis Note
对照
新生儿人成纤维细胞（SCC058）。
新生儿人成纤维细胞（SCC058）。
通过免疫细胞化学在新生儿人成纤维细胞（SCC058）中进行评价。
免疫细胞化学分析：该抗体的1：50稀释液在新生儿人成纤维细胞（SCC058）中检测到线粒体。
免疫细胞化学分析：该抗体的1：50稀释液在新生儿人成纤维细胞（SCC058）中检测到线粒体。
Application
使用经验证可用于ICC的小鼠单克隆抗体，抗线粒体抗体，克隆113-1 &Cy3偶联物检测线粒体标记物。
研究子类别
发育神经科学
细胞器&细胞标志物
发育神经科学
细胞器&细胞标志物
研究类别
干细胞研究
细胞结构
干细胞研究
细胞结构
通过免疫细胞化学在人脂肪间充质干细胞（SCC038）中进行评估。
免疫细胞化学分析：该抗体的1：50稀释液在人脂肪间充质干细胞（SCC038）中检测到线粒体。
免疫细胞化学分析：该抗体的1：50稀释液在人脂肪间充质干细胞（SCC038）中检测到线粒体。
Biochem/physiol Actions
该抗体可识别人类。抗体不与小鼠或啮齿动物反应。
Immunogen
完整的人类线粒体表面
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
在含 0.1％ 叠氮化钠和 15mg/ml BSA的 PBS 中的Cy3偶联的纯化的小鼠单克隆 IgG1。
纯化的蛋白G
Preparation Note
自收到之日起，以未稀释等分试样避光冷藏于2-8ºC，可保存 6 个月。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Jennifer A Kashatus et al.
Molecular cell, 57(3), 537-551 (2015-02-07)
Ras is mutated in up to 30% of cancers, including 90% of pancreatic ductal adenocarcinomas, causing it to be constitutively GTP-bound, and leading to activation of downstream effectors that promote a tumorigenic phenotype. As targeting Ras directly is difficult, there
Sarah Guégan et al.
Experimental dermatology, 25(10), 789-796 (2016-05-20)
Congenital melanocytic nevi (CMN) are benign proliferations that may be associated with various consequences depending on their size. They are characterized by a specific molecular signature, namely a postzygotic somatic NRAS or BRAF mutation. We have recently reported that large
Lorenzo Romero-Ramírez et al.
Journal of biomedical science, 27(1), 35-35 (2020-02-19)
Spinal cord injury (SCI) is a highly debilitating pathology without curative treatment. One of the most promising disease modifying strategies consists in the implantation of stem cells to reduce inflammation and promote neural regeneration. In the present study we tested
Marta Aguado-Garrido et al.
International journal of molecular sciences, 25(3) (2024-02-10)
The treatment of spinal cord injury (SCI) with uncultivated human bone marrow-derived stromal cells (bmSCs) prepared by negative selection has been proposed to be therapeutically superior to treatment with stem cells that were expanded in vitro. To explore their use
Jian Wang et al.
Theranostics, 12(9), 4288-4309 (2022-06-09)
Grafted astroglia/astrocytes exhibit neuroprotective effects and improve functional recovery after injury to the central nervous system. This study sought to elucidate their ability to repair spinal cord lesions and the underlying mechanisms. Methods: Complete spinal transection, transplantation of astroglia generated
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