MABN140
抗-NeuN（兔单克隆）抗体，克隆27-4
clone 27-4, from rabbit
别名:
兔抗NeuN抗体
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
27-4, monoclonal
Species reactivity:
rat, mouse
Application:
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Technique(s):
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
immunohistochemistry: suitable
western blot: suitable
Citations:
71
产品名称
抗-NeuN（兔单克隆）抗体，克隆27-4, clone 27-4, from rabbit
biological source
rabbit
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
27-4, monoclonal
species reactivity
rat, mouse
species reactivity (predicted by homology)
human (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RBFOX3(146713)
mouse ... Rbfox3(52897)
Application
抗NeuN（兔单克隆抗体），克隆27-4可检测NeuN（兔单克隆抗体）水平，&已发布&验证可用于ICC、蛋白质印迹&IHC。
研究子类别
发育神经科学
发育神经科学
研究类别
神经科学
神经科学
免疫细胞化学分析：该抗体以1:100稀释度在大鼠E18皮层和海马体原代培养物中检测到NeuN。
免疫组织化学分析：该抗体以1:400稀释度在小鼠小脑和海马组织中检测到NeuN。
免疫组织化学分析：该抗体以1:400稀释度在小鼠小脑和海马组织中检测到NeuN。
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
Analysis Note
对照
小鼠脑核提取物
小鼠脑核提取物
通过蛋白质印迹法在小鼠脑核提取物中进行评价。
蛋白质印迹分析：该抗体以1:2,000稀释度在10 µg小鼠脑核提取物中检测到NeuN。
蛋白质印迹分析：该抗体以1:2,000稀释度在10 µg小鼠脑核提取物中检测到NeuN。
General description
NeuN是一种RNA结合蛋白，属于进化上保守的Fox-1家族。它主要涉及RNA剪接。它仅存在于神经元细胞的细胞核中，但也存在于所有检验的脊椎动物的大多数CNS和PNS神经元细胞类型中。尽管NeuN蛋白的分布显然仅限于胎儿和成年大脑中的神经元核、核周和一些近端神经元过程。一些神经元在某些细胞的各个年龄段都无法识别NeuN。免疫组织化学可检测的NeuN蛋白首先出现在与神经元退出细胞周期和/或神经元终末分化开始相对应的发育时间点。免疫反应性出现在小鼠神经管中的E9.5附近，并在E12.5的整个发育中的神经系统中广泛存在。强烈的核染色表明核调节蛋白功能。但是，目前尚无关于NeuN蛋白抗原是否在远端细胞质中具有功能或在转运回细胞核之前仅在那里合成的证据。在免疫印迹上，从纯化的细胞核分离的蛋白质与全脑提取物之间没有发现差异。
观测分子量~46/48 kDa
Immunogen
对应于小鼠NeuN的重组蛋白。
Physical form
形式：纯化
纯化的兔单克隆IgG，溶于含0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05%叠氮化钠的缓冲液中。
纯化蛋白A
Preparation Note
自接收之日起，在2-8°C下可稳定保存1年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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