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Merck
CN

04936

O-(6-氯-1-苯并三氮唑-1-基)-N,N,N′,N′-四甲基脲六氟磷酸酯

≥98.0% (HPLC)

别名:

1-[双(二甲氨基)亚甲基]-5-氯苯并三唑鎓 3-氧化物六氟磷酸酯, N,N,N′,N′-四甲基-O-(6-氯-1H-苯并三氮唑-1-基)脲六氟磷酸酯, HCTU

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关于此项目

经验公式(希尔记法):
C11H15ClF6N5OP
化学文摘社编号:
分子量:
413.69
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:
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Quality Level

assay

≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Coupling Reactions

impurities

≤0.5% water

mp

185-190 °C

application(s)

peptide synthesis

functional group

amine, chloro

SMILES string

ClC1=CC=C(N([C+](N(C)C)N(C)C)N=[N+]2[O-])C2=C1.F[P-](F)(F)(F)(F)F

InChI

1S/C11H15ClN5O.F6P/c1-15(2)11(16(3)4)18-17-10-7-8(12)5-6-9(10)13-14-17;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1

InChI key

ZHHGTMQHUWDEJF-UHFFFAOYSA-N

Application

Reagent for:
Synthesis of near-infrared pH activatable fluorescent probes
Synthesis of human β-amyloid by Fmoc chemistry
Stereoselective Horner-Wadsworth-Emmons olefination
Covalent ligation of fluorescent peptides to quantum dots
Alkylation of human telomere sequence

Other Notes

固相载体上寡核苷酸串合成,用于生成多重寡核苷酸


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1A

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marine fish antimicrobial peptide, chrysophsin-1 possesses versatile biological activities but its non-selective nature restricts its therapeutic possibilities. Often small alterations in structural motifs result in significant changes in the properties of concerned proteins/peptides. We have identified GXXXXG motif in chrysophsin-1.
Hyeran Lee et al.
Bioconjugate chemistry, 22(4), 777-784 (2011-03-11)
Highly tumor selective near-infrared (NIR) pH-activatable probe was developed by conjugating pH-sensitive cyanine dye to a cyclic arginine-glycine-aspartic acid (cRGD) peptide targeting α(v)β(3) integrin (ABIR), a protein that is highly overexpressed in endothelial cells during tumor angiogenesis. The NIR pH-sensitive
Juan B Blanco-Canosa et al.
Journal of the American Chemical Society, 132(29), 10027-10033 (2010-07-06)
Water solubilized nanoparticles such as CdSe-ZnS core-shell nanocrystals (quantum dots, QDs) have great potential in bioimaging and sensing applications due to their excellent photophysical properties. However, the efficient modification of QDs with complex biomolecules represents a significant challenge. Here, we



全球贸易项目编号

货号GTIN
04936-5G-F04061833458501
04936-100G-F04061838635884
04936-25G-F04061838635891